The 102 liquidators of consequences of the Chernobyl Nuclear Accident with the unstable form of ischemic heart disease and 80 patients with the similar diagnosis which were not exposed to long influence of ionizing radiation in low dozes were examined. Character of immune mechanisms of formation of development of the unstable forms of ischemic heart disease in the liquidators of consequences of the Chernobyl Nuclear Accident was authentic amplification of spontaneous TNF-α production and increase of its contents in circulating blood. Change of production of the TNF-α contents would play an important pathogenic role in formation of the unstable forms of ischemic heart disease.
