A comparative clinical study was conducted to evaluate the diagnostic and prognostic value of the activation of proinflammatory cytokines (tumor necrosis factor TNFα, interleukins 1α: IL-1α, IL-2, IL-6, IL-8) in the pathogenesis of chronic heart failure (CHF) in geriatric patients with ischemic heart disease (IHD) and arterial hypertension. The findings suggest that the activation of cytokines (primarily TNF-α, IL-1α, IL-2) plays an important role.
