The results of screening research of analgesic activity of germanium biphosphonates with different bioligands are resulted in the article — nicotine acid (nicogerm), nicotinamide (germamid), magnesium (germacord). It is exposed in conditions of peripheral pain model, that all of them to one or another extent inhibit “acetic whrithings” development, thus germamid and germacord possesses the most expressed anaesthetic action. The study of anti-exudate action on the model of carragenin edema showed the presence of such activity in nicogerm and positive tendency in germacord. The got results convincingly dictate expedience of subsequent more deep researches of peripheral component of anaesthetic activity of germamid and study of central component of analgesic action of germacord.
