Odesa National Medical University MH of Ukraine, Odesa, Ukraine
DOI 10.54229/2226-2008-2021-6-8
Diagnosis and treatment of malignant neoplasms of the head and neck is an urgent modern problem of oncology, as there is a steady increasing of this pathology. At the same time are untimely diagnosis and frequent recurrences take place.
The purpose is to test the method of excision of the tumor of the skin of the external nose and assess its feasibility in radical surgical removal by using anemic Klein solution.
Material and methods of research: 64 patients were examined with skin neoplasms that received surgical treatment options using Klein’s anematize solution at the ENT department from 2015 to 2020 years. Patients ranged in age from 28 to 65 years, 15 women and 49 men. Patients are divided into two groups depending on the morphology of the tumor. The first group — 50 (78.2%) patients with malignant skin lesions. From this sample, 17 (34%) with basal cell carcinoma of the nasal skin and 33 (66%) with squamous cell carcinoma (G1) of the nasal skin. The second group consists of 14 (21.8%) patients with melanoma of the skin of the nose and torso. Metastasis in the deep jugular chain were diagnosed in 6 (16.7%) patients from the group of patients with melanoma.
Results of the study and discussion: observations of patients for 5 years showed a satisfactory quality of life of all patients with malignant skin tumors. No recurrence of nasal cancer in the first group was registered during the follow-up of patients. Among a group of patients with melanoma, 1 (7.1%) patient was diagnosed with recurrence in the visual organ and brain.
Conclusions:
- Clinically, skin cancer was non-aggressive, had a relatively slow growth and 100% of patients had no recurrence of cancer after surgery for 5 years (p<0.05).
- Melanoma of the skin was aggressive in a year — 1 (7.1%) patient was diagnosed recurrence in the visual organ and brain.
- The use of Klein’s solution 5 minutes before the surgery under the base of the tumor provided a pronounced hemostasis due to vasospasm and contributed to the prevention of intraoperative recurrence in 63 (98.4%) patients (p<0.05).
Key words: malignant tumors, skin of the external nose, surgical treatment, recurrences.
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