Clinico-morphological analysis of 20 placentas of women which had the syndrome of miscarriage, caused by hyperhomocysteinemia (I group) and 20 placentas of women with physiological pregnancy (II group) was made. The gestational period of the I group patients was complicated by prematue placenta and chorion detaching (20 %), abortion (25 %), chronic fetoplacental insufficiency, olygohydroamnion (10 %), fetus growth retardation (50 %).
Morphological data showed primary violation of the fetus development in patients suffering from hyperhomocysteinemia, caused and manifested themselves by placental insufficiency.