ROLE OF ENTEROHEPATIC CIRCULATION IN PATHOGENESIS OF GYNAECOLOGIC DISEASES

At a dyskinesia of biliary tracts revealed in 713 (77.2 %) patients, hormonal infringements were marked 1.9 times more often, dishormonal diseases 2.5 times, tumours — 6.9 times, than in other disorders of the digestive system. Laboratory methods revealed the holestatic syndrome 4.5 times as much in a subgroup with hormonal infringements, 4.2 times — with tumours and 5 times as much in women suffering from dishormonal diseases in comparison with the patients having inflammatory diseases of the female sphere. It is shown, that even healthy women have steroid degradation products accumulation (pseudohormones) in enterohepatic circulation leading to development of hormonal disorders.