The immobilization of food, domestic, pollen allergenes and remedies (methylene blue, novocain, acelysine — mixture of DL-lysine-acetylsalicilate and glycine) with quantitative entrappment in polymeric films for intranasal introduction was conducted. The stable at storage, with prolonged action, preparations were obtained. Enhancement of their prolongation upon the matrix — polyvinyl alcohol treatment with sodium tetraborate in different concentrations was shown. With the usage of polymeric films with allergenes entrapped, the method of intranasal specific immunotherapy of allergic rhinites was worked out.
