108 patients from 55 to 80 years suffering from arterial hypertension of different severity, II–III stages were examined. The patients were divided into male and female groups. Systolic and diastolic blood pressure, the general index of life quality, heart rate variability parameters (total power and low to high frequency ratio (LF/HF)) have been evaluated before therapy, in an acute pharmacological test and after 4-weeks’ therapy with Amlodipin. The results showed positive increase in general index of life quality in both groups with higher degree in the female group. The target level of blood pressure is reached in the female group. Insufficient hypotensive effect of Amlodipine was found in the male group.
