In acute experiments on rats with a modelled brain mechanical trauma, the decreasing in the weight of spleen, thymus along with simultaneous increasing in the weight of suprarenal glands and enlargement of the cortical and medullar layers were seen. It was established that L-deprenyl (0.1 and 0.5 mg/kg, i/р.) and pentoxyphyllin (25.0 and 100.0 mg/kg, i.p.) prevented trauma-induced deteriorations while combined usage of drugs caused potentiated therapeutic effect.
