The distribution of 14C-riboflavine was studied in mice after different ways of its introduction. It was demonstrated, that any of the studied methods of introduction insignificantly influenced bioavailability (for intramuscular introduction it reached 90%) and parameters of preparation distribution processes in organs and tissues of mice. A substantial increase in biological availability of preparation (~18 times) for the experimental animals’ eye structures at intravenous introduction became a distinctive feature of pharmacokinetics.
