It was established in the studies made that the content of dien conjugates and malonic dialdehide in the liver and blood serum of mature female rats under physiological conditions was significantly higher than the same indices of the male rats. The intake of alcohol by female and male rats before coupulation intensified formation of POL products, especially in female rats. Ontogenesis of female and male generation which is born from alcohol-consuming rats shows that content of POL products was significantly higher than the same indices of the same age control. It was suggest that these animals had considerably reduced level of the organism’s endogenic non-spesific resistancy.
