Over the past decade’s adverse demographic situation in Ukraine population associated with the deterioration of the reproductive health. There are infertility and somatic diseases of the adult population in the first place; secondly, it’s an unfavorable progress of pregnancy (exacerbation of somatic diseases of the pregnant women, the impact of negative environmental factors, miscarriages, congenital abnormalities and placental dysfunction (PD)) which leads to the birth of children with a probable imbalance in functioning of organs and systems.
Somatic diseases of children born from mothers with PD (cardiovascular, respiratory, nervous, immune systems, etc.) it have been shown on the experiment and clinic data already. However, there is less analysis devoted to the functioning of the reproductive system of such children for today. This is the purpose of our research in the future. All diseases imply the treatment of patients; however, it should be not harm to the unborn child.
These characteristics have gravidoprotectors, these are drugs that affect the placental complex. At SI “V. Danilevsky Institute for Endocrine Pathology Problems of NAMS of Ukraine”, the pharmaceutical composition which contains active pharmaceutical ingredients (amino and dicarboxylic acids, vitamins and vasodilators) for the prevention of the PD effects on the reproductive system of adult offspring has been developed.