Introduction. The question of the prolonged QTc interval in patients with hypertension, as one of the predictors of cardiovascular complications and premature death, attracts attention due to inadequate study.
Materials and methods. The frequency of occurrence of types of daily blood pressure profile depending on the specific gravity of the prolonged QTc interval in 87 patients with hypertension was studied. Depending on the duration of the prolonged interval QTc per day were allocated three groups: group 1 — the term prolonged by day of the interval QTc from 0 to 33.3%, group 2 — from 33.4 to 66.6%, group 3 — from 66.6 to 100%. In each group, the share of types of daily profile of SBP and DBP was determined.
Results. The frequency of occurrence of type of daily profile of SBP in the groups of the prolonged QTc interval in patients with hypertension is as follows: the largest group consists of patients with a daily profile SBP Dipper — 45% and Non-dipper — 41%, the smallest — with the profile of SBP Over-dipper — 5% and night-picker — 9% of the total number of surveyed. In the prolonged QTc groups, in the analysis of the distribution of DBP profiles, the largest group of patients with the profile of DBP Dipper is 38%, almost at the level of the Over-dipper group — 30% and Non-dipper — 29%, and the lowest is the Night-picker group — 3%.
Discussion. The given results are caused by different regulation of SBP and DBP, therefore the different frequency of their daily profile at our analysis is received. So, one cannot but pay attention to SBP.
Conclusions. With an increase in the number of the group of the prolonged interval QTc per day, on the background of the decrease in the frequency of the occurrence of the daily profile of the Dipper SBP, an increase in the proportion of the Non-Dipper SBP profile is noted.