ETIOPATHOGENETIC FACTORS OF DEVELOPMENT OF ADENOMYOSIS AND ENDOMETRIAL HYPERPLASIA IN WOMEN OF REPRODUCTIVE AGE

The problem of adenomyosis and endometrial hyperplasia is of particular relevance to patients of reproductive age since these diseases are accompanied by significant violations of the menstrual and generative functions.

Objective. To study the risk factors for the development of adenomyosis, endometrial hyperplasia and adenomyosis in conjunction with hyperplastic endometrial processes in women of reproductive age.

Materials and methods. Clinical and statistical analysis of 135 women of reproductive age with benign pathology of endometrium and myometrium, made up the main group. The main group is divided into subgroups: I subgroup — 45 patients with adenomyosis, II subgroup — 45 patients with endometrial hyperplasia, III subgroup — 45 women with a combined pathology. Control group — 30 gynecologically healthy non-pregnant women of reproductive age.

This article presents the data that includes the results of clinical-statistical analysis among reproductive-age women with the benign pathology of endo — and myometrium. The risk factors of development of adenomyosis and hyperplasia in investigated group are determined. Those are: complicated heredity, high frequency of the clinical abortions, spontaneous miscarriages, pathological deliveries in the past. The low index of health is observed in such category of women: high rate of gynaecological or extragenital pathology, 3 times higher frequency of child’s and respiratory illnesses, the surgical intervention on uterus and ovariums promotes the progress of the pathology of endo- and myometrium. It is the fact, that the most frequent clinical manifestations of adenomyosis and hyperplasia of endometrium are pain and hemorrhagic syndrome.