Research of non-linearity of heart rate variability is conducted by the method of M-indices in patients with chronic ischemic heart disease (IHD). Patients, depending on the presence of depression, were divided in to 2 groups. Initially in the group of patients with depression the indices of non-linearity were lower than in the group without depression. With use of the pathogenic IHD treatment increasing of M-indices was registered in both groups. Taking into account the kept distinctions between groups, patients with depression require antidepressant prescription.
