PHARMACOLOGICAL REGULATION OF THE FUNCTIONS OF THE HYDROLYTICAL AND TRANSPORT SYSTEMS FOR DIMERS IN THE SMALL INTESTINE OF THE IRRADIATED RATS’ POSTERITY

The goal of research was the investigation of the silimarine-containing medicine’s effect (legalon and extract of the spotty rastoropsha fruits) on the hydrolysis and transport of the maltose and glycil-glycine in the small intestine of the irradiated rats’ posterity.

The discrepancy of the animal weight to the small intestine functional activity was found. It was shown that presence of the spotty rastoropsha fruits extract in the incubation medium decreased the accumulation of the M-glucose in the intact group and increased – in the irradiated rats’ posterity group (by 22 % and 30.5 % accordingly), and didn’t effect on the accumulation of “peptide” glycine.

Legalon presence didn’t effect on the accumulation of the M-glucose in both groups.