The aim is to substantiate the effectiveness and methodological completeness of the results of hygienic regulation in water of simple oligoester of the technical name “Laproly” of grades 2102 and 3603-2-12 as basic substances and products of their hydrolytic destruction and transformation of 2-methoxyethanol and methylcarbitol on the basis of determining the leading links of the mechanism of action on the organism of warm-blooded animals and the influence on the organoleptic properties of water and the sanitary regime of water bodies.
Results. According to the results of work, based on the principles of evidence-based medicine, the following is defined.
Simple oligoesters of the technical name “Laproly” of grades 2102 and 3603-2-12 in aqueous solutions are highly stable substances capable of undergoing hydrolytic degradation and transformation with the formation of a wide range of dangerous products: ethers (methylcarbitol and 2-methoxyethanol), alcohols (methanol, ethanol, isobutanol and isopropanol), ketones (acetone and methyl ethyl ketone), aldehydes (acetic and propionic). The most common among products of hydrolytic degradation and transformation of simple oligoesters are 2-methoxyethanol and methylcarbitol.
Conclusions. 1. The program of studies included sections of organoleptic studies, study of the influence of research objects on the sanitary regime of water bodies and the division of sanitary and toxicological studies on warm-blooded animals, which fully meets the requirements of normative and methodological documents regulating research on the problem of substantiation and development of official state hygienic standards — the maximum permissible concentrations (MPC) of harmful chemical compounds for water in reservoirs. 2. For the first time, the maximum permissible concentrations of new surface-active substances of grades 2102 and 3603-2-12 and the main products of their hydrolytic destruction and transformation of 2-methoxyethanol and methylcarbitol for water of reservoirs have been scientifically substantiated.