The vitamin D deficiency is widely spread not only in Ukraine but all over the world. Lower level of vitamin D increases the risk of cardiovascular complications and fragility fractures, which increase th risk of injury, contribute to early disability and mortality.
Аim. To study the frequency of deficiency and insufficiency of vitamin D working at women with metabolic syndrome under unfavourable production conditions.
Materials and methods. We examined 46 women employed in harmful working conditions and 10 women who do not employed in harmful working conditions with more than 20 years work experience. There was conducted anthropometry and studied of lipid, carbohydrate and phosphorus-calcium exchange and the level of 25(OH)D.
Results. We got low levels of 25(OН)D (of 14.81±1.75) in the serum of women with metabolic syndrome employed in harmful working conditions, in contrast with healthy women (21.62±3.33) who do not employed in harmful working conditions (p<0.05). The results showed a strong inverse correlation between body mass index and level of 25(OH)D (r=-0.7; p=0.008), and negative direct correlasion between the level of 25(OH)D and mineral bone density (r=-0.55; p=0.012).
Conclusion. The prevalence of vitamin D deficiency among this category of people is 97.7%. There was established inverse correlation between 25(OH)D and body mass index and direct correlation between level of 25(OH)D and mineral density of bone tissue. Harmful production factors (chemical and physical) cause the development of D-deficient states.