Atopic dermatitis (AD) is a genetically determined, chronic, inflammatory disease of the skin, which affected 10–30 % of children.
The purpose of research is the study of the clinical manifestations of atopic dermatitis in children with specification of age characteristics and dynamics of manifestations.
The study included 110 children with a diagnosis of atopic dermatitis in age from 2 months to 12 years.
The localization and morphology of the rash depended on the age of the patients. In 87 children it was noted the early onset of the disease in the first two years of life, and the clinical manifestations of AD corresponded to the so-called infant phase of the disease, with mild and moderate courses. In the group of children older than two years, the clinical manifestations corresponded to the childhood phase of the disease with a typical morphology and localization of the rash. In the childhood phase of AD, inflammatory changes were less manifested, but the course of the disease was more persistent with frequent recurrences. In young children, pruritus appeared mainly against AD exacerbation and it was absent in the stage of remission. There was a tendency to increase itching with age, especially at night. The itching often remained in the period of remission, but its intensity decreased. The dryness of the skin increased with age. It was noted not only in the lesions, but also outside the affected areas and was observed in the vast majority of patients. Association of AD with food allergy was more often observed in children of the first two years of life, which caused a more severe course of the disease.