Стремительное увеличение в клинической практике случаев полирезистентной инфекции, связанной, в частности, с Pseudomonas aeruginosa, делает актуальным поиск и внедрение альтернативных и вспомогательных методов терапии. Одним из перспективных направлений является возобновление интереса к терапии бактериофагами. В статье описан клинический случай успешной терапии бактериофагами местной хирургической инфекции, вызванной Pseudomonas aeruginosa.
Patient T., aged 55, was hospitalized in the surgical department of the Lviv Hospital in rail transport with trophic chronic ulcer of the left leg. The development of disease associated with thrombophlebitis more than 10 years ago.
Favorable conditions of Pseudomonas infection in the above clinical case was probably the major defects of the skin with a local trophic infringement and, accordingly, reduced resistance. Local antiseptic therapy did not provide good clinical efficacy, which led to search and used fundamentally different methods of treatment.
The rapid rise in the incidence of multidrug-resistant infections in surgical clinics updates issues and the search for alternative therapeutic approaches. This clinical case demonstrated sufficient clinical efficacy in the treatment phagetherpy local infections caused by multidrug-resistant gram-negative bacteria Pseudomonas aeruginosa. There is a need to conduct clinical trials wide potential opportunities and threats phagetherapy for the inclusion of this type of therapy as standard treatment of resistant infections.