Immunohistochemical research of basic clones of immune cells, that are situated in the central (thymus) and peripheral organs (spleen, mesenterial lymph nodes) of the immune system in the rats was conducted during experimental acute toxic hepatitis induced by carbon tetrachloride. It was shown that toxic liver’s affection leads to disbalance of basic components of immunity. This makes more active macrophagial and humoral components of immune system, which is manifested in increasing of amount of macrophages and plasmatic cells in different functional zones of immune organs. Expressed changes of Т-cellular population are characterized by relative impoverishment of Т-zone and decreasing of helper-suppressor index.
