Most scientific papers, which examined the prenatal development of the medulla oblongata performed on animals and applies research of individual cores or structures without a comprehensive study of all of the medulla oblongata, so there is a need for more detailed study of the histological structure and topography of neural systems medulla to establish its normal structure in fetus at different times of gestation.
The research was conducted on 15 stillbirths, gestational age 39–40 weeks who died from causes not related to disease brain or spinal cord. Preparations medulla after fixation and production of paraffin blocks were stained with hematoxylin-eosin, toluidine blue and Van — Gieson.
The paper presents the results of research histometry parameters and structure of the medulla oblongata in human fetuses 39–40 weeks of fetal development. There are established the nucleus of the medulla oblongata, and the form and degree of differentiation of neurons.
In the sensory nuclei of cranial nerves neurons studied two types of homogeneous eosinophilic cytoplasm and containing a perikaryon basophilic substance. The density of neural stem cells in the ventral part of the neuroepithelium greater than the lateral and dorsal parts.
In the future, further development is planned to establish patterns and determine the topography of neurons and glia cells via the expression of immune-histochemical markers.