The influence of the applications of lithocholic acid (LCA) upon the oral mucous membrane (cheek and tongue), dosed at 0.35 mg/kg, was studied at the experiment with white rats. The reduction of the activity of lysozyme, urease to less degree, and the growth of the disbiosis extent (at the determination with Levitsky’s enzymatic method by urease/lysozyme ratio), was more pronounced in cheek in 24 hrs. LCA does not cause disbiosis development in the blood serum.
