Research aim: clinical and microbiological ground for local application of the “Apident” gel in the complex treatment of generalized periodontitis.
Material and methods. Clinical researches were conducted on the 28 patients with chronic generalized periodontitis (ChGP) and 14 healthy people. All patients were devided into 3 groups: 1 — control (healthy patients), 2 — basic group, patients with ChGP having complex therapy with a local treatment by a new gel “Apident”, 3 — comparison group, patients with ChGP having a traditional therapy. The clinical tests included the visual-instrumental researches and index estimation of state of parodontium and oral cavity. Microbiological researches of 2 biotopes: oral fluid and gingival fluid of parodontal pockets or dentogingival depression were conducted before and after the medical treatment. A qualitative and quantitative composition of microflora of biotopes at ChGP was determined.
Results. The application of the “Apident” gel in the complex medical treatment of patients with ChGP caused the positive changes in clinical symptoms and state of parodontal tissues, that found the reflection in the decline of hygienic and parodontal indexes. Recovery terms in ChGP patients in the basic group reduced up to 2–8 days.
In the microbiological researches on background of changed normal microflora in the oral fluid and content of parodontal pockets in ChGP patients revealed increase of anaerobic bacteroids, fusiformis and prevotellas. In case of local treatment by the “Apident” gel on the 14th day after the beginning of medical treatment the considerable decline of pathogenic microflora in researched biotopes of patients with ChGP took place, that testifies to the bactericidal action of preparation.
Conclusion. Local application of the “Apident” gel in the complex therapy inflammatory parodontium diseases promotes efficiency of medical treatment and reduces recovery terms.
The “Apident” gel shows bacterioststic action, lowering the quantity of pathogenic microorganisms in the otal cavity, removing violations of microbiocenosis of the sulcus.