Chronic diffuse liver diseases often occur with similar clinical symptoms and the same changes of laboratory parameters. Therefore, the objectification of differential diagnosis of various forms of liver disease is an urgent task.
Objective of the study was to study the possibilities of mapping the distribution of values polarization ellipticity points polycrystalline films of microscopic images of blood plasma in the differential diagnosis of nonalcoholic fatty liver disease (NAFLD) and chronic hepatitis (CH).
Material and methods. The study involved 50 patients with NAFLD, made up the first group. The second group included 50 patients with nonviral CH. The control group consisted of 30 healthy individuals representative by age and gender to the studied groups. As objects of experimental research it was used a series of polycrystalline films of plasma surveyed by laser Stokes-polarimeter.
Results. The analysis of the data revealed that the strength of two-dimensional laser polarization mapping ellipticity of polarization to differentiate various pathologies of the liver (NAFLD and CH) is maximum for statistical points of the 2nd and 3rd order. For statistical moment of the 2nd order Se=80% and Sp=74%. For statistical moment 3rd order Se=84% and Sp=78%. According to this, accuracy of the method is Ac=78–82%.
Conclusion. Within the statistical analysis of the structure (ellipticity divisions) polarization-inhomogeneous microscopic images of polycrystalline networks albumin film plasma with definition of the most susceptible to studied liver disease statistical parameters (statistical moments of the 2nd and 3rd order) microscopic image of polycrystalline films of blood plasma.