Introduction. Investigations of antioxidant defense are of particular interest. Allotransplantation is a stress factor for the organism, which results in oxidation of remanufactured components of available membranes of cells that leads to forming superoxide anions. Superoxide dismutase and catalase is one of the most important components of the antioxidant defense system in mammals.
Materials and methods. The 3 types of surgical intervention were carried out: 1 — allograft of embryonic muscle tissue; 2 — transplantation of muscle tissue taken from a rat of the same litter; 3 — false operation. Superoxide dismutase and catalase activities were determined in tissues of the donor and recipient.
Conclusions. Thus, alotransplantantation of the femoral muscle stabilizes activity of SOD on the first day of the study; changes that occurred later were induced by the effect of surgery. On the third day of the study transplantated abdominal muscle affects the embryo as a stimulant mechanism with the struggle with formed superoxides. Allotransplantation of the hip and abdominal embryonic muscle tissue leads to stabilization of catalase activity in tissues of the adult rat.