In acute experiments on male Wistar rats it was shown that facilitative action caused by bacterial lypopolysaccharide (LPS) upon generalized penicillin-induced seizures (3.0 mln IU/kg, i. p.), which is observed in 4 h from the moment of LPS (“Pirogenal”, 1.0 mg/kg, i. p.) administration, is blocked by transcranial magnetic stimulation (TMS, 1.5 Tl, 20 impulses) as well as by electrical paleocerebellar stimulations (100–300 Hz, 10–20 trials of stimulations). TMS (1.5 Tl, 10 impulses) caused the pronounced antiepileptic action in 12 h from the moment of LPS administration.
