SUBCHRONIC TOXICITY STUDY OF THE DRUG “ALTSINARA”: EFFECT ON FUNCTIONAL STATUS AND LABORATORY PARAMETERS IN RATS

There were presented the results of experimental study of the drug Altsinarasafety, tablets for oral use made in the private joint stock company PAO NPC Borschagovsky KhFZ.

Study of toxicological parameters of Altsinara after repeated administration determined that under the conditions of the subchronic application of the drug in doses of 50, 100 and 500 mg/kg in rats this remedy does not cause the death of animals, has no toxic effect on the common state, behavior and the dynamics of body weight, does not cause significant differences in terms of laboratory analysis of urine and blood, does not affect on the indicators of the functional state of the hepatobiliary and urinary systems.

Thus, the results of the study indicate that Altsinara is a safe drug for human, renders no toxic effects on the body not only with single, but also during the long-term usage in extremely high doses.