In the course of our study there were revealed signs of endogenous intoxication in children suffering from overweight and obesity, which is a consequence of dysbiotic disorders that inhibit factor FIAF, and in its turn are the main reason for the increased synthesis and accumulation of fat mass. The presence of dysbiosis in the examined children were also confirmed by the low activity of lysozyme and a sharp increase in urease activity. The fact of abnormal relation of microbiota in the organism of children with overweight and obesity may be a new trend in the integrated program of treatment of this disease.
