PHARMACOLOGICAL EFFECTS OF SOME PHYTOAGENTS IN THE BILE PRESENCE ON THE HYDROLYSIS AND TRANSPORT OF GLYCIL-GLYCINE IN THE IRRADIATED RATS POSTERITY SMALL INTESTINE

It was shown that the presence of bile in the incubation medium leads to the higher level of the glycil-glycine hydrolysis and transport into the small intestine of the irradiated rats posterity. The best effect of the bile in the optimisation of the glycil-glycine transport was detected in the presence of the summary extract of milk thistle fruits: in this case the level of substrate transport was 2 times as much than in the control group simultaneously with the stabilization of the process. The modificative activity of bile on the pharmacological effects of milk thistle and calendula summary extracts and legalon in the irradiated rats small intestine posterity was detected.