MODELLING OF PARODENTIUM PATHOLOGY IN RATS UNDER TOXIC ESTROGENIC INSUFFICIENCY CONDITIONS
Ye. К. Тkatchenko, О. I. Skyba, О. M. Voskresensky
Keywords: pathology of parodentium, estrogenic insufficiency, clotrimazol, cytochrom P450-aromathaze, mineral metabolism, lipid peroxidation
The method of parodentium pathology modelling, like human periodontitis, was introduced in experiment on 18 white male-rats, under estrogenic insufficiency conditions, creating by chronic peroral Clotrimazol administration — inhibitor of cytochrom P450-aromataze.