While conducting the study it was evaluated the rationality of antibiotic prescriptions for patients with respiratory tract infections in accordance with the modern guidelines and recommendations.
It have been shown protected aminopenicillins (amoxicillin/clavulanic acid) were prescribed in 1.85% of case histories, cephalosporins of the III generation (ceftriaxone) were in 46.30%; macrolides (azithromycin, roxithromycin) were in 12.96% and 1.85% cases respectively. Respiratory fluoroquinolones mostly were prescribed as alternative drugs: levofloxacin was administered in 11.11% of cases. In 17% of cases has been prescribed a combined antibiotic therapy, the leading combination was ceftriaxone / azithromycin — 71.43%. As monotherapy, the most frequently prescriptions were ceftriaxone (42.42%) and levofloxacin (21.21%).
The analysis of antibiotic treatment showed that the doctoral prescriptions is according to the recommendations and the standards of treatment. To decrease the frequency of irrational use of antimicrobial drugs for lower respiratory tract infections it should be rationally to conduct the pharmaceutical care of physician by clinical pharmacist to increase the awareness of physicians about the evidence base of antibiotic therapy, pharmacodynamic and pharmacokinetic features of antibiotics, to form the system of drug monitoring.