The features of clinical course of pregnancy and laboratory estimation of the chorion-embryo, phetal-placental complex condition in 163 women which matured fetus with congenital malformations are studied. Congenital malformations of fetus were first discovered in the first trimester in 35 (25,7 %) supervisions, in the second — in 82 (60,3 %), in the third — in 19 (13,97 %). Determination of these anamnestic data of women which gave birth to children with congenital malformations serves as an early prognostic criterion of their development.The clinical course of pregnancy in women which carry children with congenital malformations has certain features by the trimesters of gestation: accompanied with pathology of amniotic fluid, violation of the fetal-placental circulation, placental disfunction.
