Influence of different doses of nicotinamide, its combinations with thiamine (В1) and other group B vitamins on the biosynthesis of nicotinamide coenzymes in the liver and the blood of the F1 line mice (CBA x Black). It was established that between the vitamin В1 and vitamin PP (nicotinamide) there is optimum ratio in relation to the nicotinamide coenzymes biosynthesis in the organs of mice, which little depends on the dose of nicotinamide. Combination of nicotinamide with other vitamins of group B allows to multiply considerably its ability to transform into coenzyme forms. Efficiency of vitamin complexes in these indices grows with multiplying the amount of components in them, but for a 6-component (B1, flavine mononucleotide, nicotinamide, B3, B6, lipoic acid) achieves a limit.
