CYTOKINE THERAPY BY THE GRANULOCYTE COLONY-STIMULATING FACTOR AND RECOMBINANT ERYTHROPOIETIN AS ALTERNATIVE STRATEGY IN NON-CORONAROGENIC CARDIOMYOPATHY CONDITION

Data that the granulocyte colony-stimulating growth factor induces regenerative-plastic processes in the myocardium under conditions of experimental modelling of adriblastin cardiomyopathy at mice are presented in the work, thus this effect is more pronounced at early introduction of preparation. The use of recombinant erythropoietin on that model strengthens stromal-parenchymal co-operation in the myocardium and normalizes metabolism of cardiomyocytes. Preventive introduction of preparation worsens the state of the cardiac muscle.