ESR (erythrocyte sedimentation rate) and levels of C-reactive protein (СRP), cytokines IL-1β and IL-4, as well as the FAS-mediated apoptosis CD95+ marker level have been investigated for women having autoimmune thyroiditis (AIT) during the childbearing and menopausal age. Correlations between the obtained values have been analyzed. It was determined that significant age-specific distinctions exist in levels of CRP and its associative relations with anti-inflammatory cytokine and apoptosis. These results can indicate an existence of age-specific features in the AIT development mechanism for women and also can explain a considerable increase of autoimmune thyroiditis level during the menopausal age.
