One of the major etiological factors of chronic obstructive diseases of lungs (CODL) is smoking. The article presents materials of studying of some anti-inflammatory citokines in the blood serum and bronchial lavage in patients suffering from CODL are presented. It is established that the long experience of smoking is a risk factor of increase of system and regionar (endobronchial) citokine potential in CODL patients, which is considered as an important pathogenetic mechanism of synchronisation and progressing of nonspecific inflammatory disease of lungs.
