It was established that experimental hypo- and hyperthyreosis in the rat-males is accompanied with infringement of the quantity of reaction-capable protein and non-protein sulfhidril and thiol-disulfide groups. Thiol-dependent mechanism of disturbance of non-enzymatic redox reactions with experimental hypo- and hyperthyreosis is explained by a “paradoxal” ability of the thiol-disulfide system components: in dependence on the character of the thyroid state they function with a prevalence of reduction or oxidation form of thiols in proteins and low-molecular compounds.
