CHANGE OF LIPID AND CARBOHYDRATE METABOLISM AFTER THE SLEEVE GASTRECTOMY

Introduction. In many countries of the world the sharp increase in patients with excessive body weight is observed. Special bariatric operations allow to achieve essential decrease in body weight and improvement of quality life, and they also treat from a metabolic syndrome. The sleeve gastrectomy is rather efficient method of obesity treatment.

The aim. Studying change of carbohydrate and lipid metabolism in patients with morbid obesity after sleeve gastrectomy.

Materials and methods. From 2007 to 2013 in the clinic sleeve gastrectomy was executed in 102 patients with morbid obesity. Weight of patients was from 89 to 192 kg, index of body weight (IBW) fluctuated from 38 to 56 kg/m2. The remote results studied in terms 3, 6, 12, 18, 24 months.

Results. Average weight of patients in 6 months decreased from (124.3±9.6) to (91.2±11.3) kg (p<0.01). The index of body weight decreased from (44.7±6.8) to (33.4±5.9) kg/m2 (p<0.01). Biochemical researches of metabolism in 12 months after the operation showed reliable decrease in blood glucose level from (6.5±1.1) to (4.7±0.8) mmol/l (p<0.05). We also traced influence of physical exercises on a carbohydrate and lipid metabolism.

Conclusions. Our researches showed that the laparoscopic sleeve gastrectomy not only leads to weight reduction but also normalizes lipid and carbohydrate metabolism.