Actuality. Wide application of antibiotics in medicine is accompanied with spreading antibiotic-resistent strains of staphylococcus. That is why there is conducted a constant search for new effective anti-staphylococcal medicines.
Purpose of research — studying anti-staphylococcal activity of the coordination compounds of metals — cobalt, germanium, tin with the citric acid on staphylococcus strains: Staphylococcus aureus ATSS 25923, Staphylococcus aureus 2781, Staphylococcus aureus Cunda.
Materials and methods. For studying sensitivity it was used a method of serial dilution in the fluid culture — the minimal concentrations of compounds were determined. Measuring turbidity of bacterial suspensions was conducted on densitometer, and value of optical density of suspension were interpreted by Mac-Farland turbidity unit (McF).
Results of research. The examined compounds supressed growth of strains of Staphylococcus aureus, possessing a different level of antibiotic resistance. The cobalt-containing compound revealed high antimicrobial activity.