Background. Chronometric tests are rapid preliminary methods of hemostasis diagnosis. However, the development of thrombophilia can occur with normal coagulometric tests, therefore the coagulation screening not always allows estimating the risk of thrombosis.
Objectives. To analyze 4 coagulometric tests in order to identify the most appropriate methods for preliminary diagnosis of the hemostasis state in atherothrombotic ischemic stroke and cardioembolic ischemic stroke with atrial fibrillation.
Methods. For the chronometric tests performance kits and reagents of “Renam”Belarus were used.
Results. For the majority of patients of both groups, prothrombin time, activated partial thromboplastin time and thrombin time were within the normal range, however, the minority of patients had significantly extended clotting time. The results of ancystron time test confirmed the thrombophilia risk in both groups of patients. For atherothrombotic ischemic stroke ancystron time decreased by 26%, for cardioembolic ischemic stroke with atrial fibrillation — by 32 % relative to donors.
Conclusions. To identify the characteristics of the disorders in the hemostatic system of patients with atherothrombotic ischemic stroke and patients with cardioembolic ischemic stroke with atrial fibrillation the most appropriate is ancystron time test. The tendency toward lengthening of clotting time in “prothrombin time”, “activated partial thromboplastin time” and “thrombin time” tests may be due to the presence of non-physiological inhibitors of coagulation cascade, formed in the circulation as a result of the disease.