EFFICIENCY OF CORVITIN IN NORMALISATION OF EYE BLOOD SUPPLY AND AQUEOUS HUMOR DYNAMICS IN GLAUCOMA MODEL

Quercetin-containing preparation corvitin acted on NO-dependent mechanisms in animals with glaucoma model and significantly influenced eye blood supply and hydrodynamics. Two week application of corvitin by fraction instillations into the conjunctive sack twice improved decreased eye blood flow. Aqueous humor (AH) dynamics were also normalized. Outflow facility of AH was increased by 58%, inflow — by 52%, intraocular pressure was decreased by 14%. The influence of corvitin was stable and keeps for, at least, 15 days.