STRUCTURAL AND FUNCTIONAL CHANGES OF LEFT VENTRICLE IN PATIENTS WITH HYPERTENSION AND DIABETES TYPE 2

Actuality. The results of epidemiologic research confirm the growth of morbidity and mortality from cardiovascular diseases, in particular, from arterial hypertension. Co morbidity of arterial hypertension and diabetes type 2 becomes more relevant for modern medicine due to similarity in pathogenic mechanisms of development. Changes in the cardiovascular system in these patients are consistent and are characterized by progressive disorders in structure and function.

The aim of this study was to evaluate the performance cardiohemodynamics and type of diastolic dysfunction in patients with hypertension and diabetes type 2.

Materials and methods. We examined 105 patients with arterial hypertension who were divided into groups depending on the presence of type 2 diabetes mellitus. All patients with arterial hypertension were divided into 2 groups: the 1st one — patients with arterial hypertension and concomitant type 2 diabetes mellitus (n=75), the 2nd one — patients with arterial hypertension without concomitant type 2 diabetes mellitus (n=30). The average age of the arterial hypertension patients with concomitant type 2 diabetes mellitus was (63.34±2.11) years, and in the 2nd group — (65.22±1.37). The control group included 25 healthy people.

Echocardiographic studies were performed by the standard method (J. Feigenbaum, 1999) on the ultrasound machine RADMIR (Ultima PRO 30) (Kharkiv,Ukraine).

Conclusions. According to echocardiography in patients with combined hypertension and diabetes type 2 there is an increase in left ventricular mass by 10.2% and the thickness of the posterior wall of the left ventricle by 2.7%.

In hypertensive patients with diabetes type 2 there are observed: increased incidence of diastolic dysfunction by type 2 (violation of relaxation) (37.3%).