Introduction. The problem of treating genital diseases relevant to the world of medicine andUkraine. Genital Chlamydia is the most common among the diseases that are transmitted sexually. Chlamydial infection is characterized by long persistent course, damage of the eye, respiratory system, joints, tissues of digestive and nervous systems etc.
Objective. Analysis of effective substances with antichlamydial action in domestic and foreign production suppositories, registered and listed in the National List of drugs and presenting own innovative developments — vaginal suppositories with Flurenizide, made in Ukraine.
Materials and methods. Scientific, legal, regulatory and prescriptive information of Ministry of Health of Ukraine on safety, pharmacological effects of substances in the vaginal suppositories, their interaction with oher drugs which provided in the protocols of care for patients with chlamydia.
Results and discussion. An important role in the causal treatment of urogenital chlamydial infection have mostly antibiotics tetracycline, macrolides and sulfanilamides drugs. In “Formulary’s use of drugs in obstetrics and gynecology” identified the main groups of drugs with proven efficacy and safety for human health. For the first time in Formular (subgroup 1.5. Other antimicrobial and antiseptic drugs) introduced a Ukrainian drug of new class (class fluorene) — Flurenizide in the dosage form of vaginal suppositories (ATC GO1A X10). The main pharmaco-therapeutic effects of Flurenizide — anti microbial (anti chlamydial, antituberculous), immunomodulatory.
Conclusions. Antichlamydial substance in suppositories of chemical compounds belongs to different classes and have significant side effects on the human body. Flurenizide fundamentally different from the active substances in antichlamydial drugs by the chemical structure, the variety spectrum and safety. “Vaginal suppositories of 0.1 g Flurenizide” are used to treat chlamydia during 2001–2011. They can be combined with all of the symptomatic drugs and antibiotics for systemic use.