The changes of TNF-α and endotoxin-core antibodies IgG in arterial hypertensive patients (AH) dependently on disease severity and intestinal disbacteriosis grades were evaluated. Target-organs’ damage is accompanied with significantly more often ІІІ–ІV degree disbacteriosis appearance 4.3 times and TNF-α plasma rising by 1.3–1.6 times as much. Endotoxin-core antibodies IgG level depends on disbacteriosis severity, chronic heart failure onset, correlates with TNF-α level and does not depend on AH severity.
