THE ROLE OF FUNCTIONAL CONDITION DISTURBANCES OF PEROXIDE-ANTIOXIDANT SYSTEM IN GUINEA PIGS’ SPLEEN IN ALLERGIC ALVEOLITIS PATHOGENESIS AND THEIR CORRECTION WITH THIOTRIASOLINE

The work represents the process of dienic conjugates and malonic dialdehyde content’ elevation and the decrease of activity of superoxydedismutase, catalase, peroxidase and ceruloplsmin in the spleen, in particular, on the 54th, 64th day of experimental allergic alveolitis development. The application of Thiotriasolin causes the decrease of PLO products formation, and stimulates the antioxidant system ferments activity, which testifies to its antioxidant correcting influence upon the investigated indices.