The effect of different classes of antiarrhythmic drugs on the duration of the corrected QT interval (QTc) was studied in 108 patients suffering from permanent atrial fibrillation (PAF). Therapy was based on the recommendations of the Working Group on cardiac rhythm disturbances of the Association of Cardiologists of Ukraine (2009). It was revealed that therapy with beta-blockers, amiodarone or calcium channel blockers led to QTc prolongation, therapy of beta-blockers and amiodarone combination — to oscillatory changes in the duration of QTc interval with a tendency to prolongation.
