An increase of the concentration of the blood plasma interleukin-1β from (37.30±2.52) to (70.30±2.07) pg/ml (р < 0,001) and development of the syndrome of the urinary loss of sodium ions with a growth of the excretion and clearance of the cation under study have been established in experiments on 40 albino nonliner male rats with the body weight 0.16–0.20 kg under the conditions of hyposodium dietary intake in 2 hrs of simulating tissue hypoxia after introducing 2.4-dinitrophenole. The interleukin-1β manifested reliable correlation dependencies with interleukin-6, tumor necrosis factor-a, excretion and clearance of sodium ions that is demonstrated by means of the multivariate regression analysis.
