Introduction. The mechanism of neuro-vegetative disturbances formation in descendants born from Chornobyls’ AES accident consequences liquidators (CBChAESACL) is very complicated. According to different authors their development connected with autonomic nervous system certain branches dysbalance, especially its central branch — the reticular-limbic complex. Thus, the patients with neuro-vegetative disturbances treatment and rehabilitation should consider both vegetative and energetic processes in CNS correction. Nobody studied the efficacy of cytoflavin possessing a multimodal action in CBChAESACL complex neuro-vegetaive disturbances treatment.
The aim of the work is cytoflavin clinical efficiency investigation in CBChAESACL with neuro-vegetative disturbances complex treatment.
Methods. The results of CBChAESACL with vegetative-vascular dystonia are given. Metabolic drug cytoflavin possessing a cytoprotective effect was additionally included in their complex treatment. Lipoic acid was administered to the control group of patients for the better estimation of the cytoflavin efficacy.
Results. One could observe the following neuro-psychic disorders in patients: astheno-neurotic syndrome, cognitive disorders of light and moderate degrees, both psychooranic and cephalgic syndromes, vegetative dysfunctions and innate disorders of development. Cytoflavin resulted in significant diminishing of vegetative disorders clinical manifestation. It processed both the oxidizing phosphorylation and free-radical lipids oxidization improvement together with intracranial hemodynamic indexes normalization.
Conclusion. Cytoflavin use in CBChAESACL with neuro-vegetative disorders was shown to induce their earlier and complete improvement compared to the same effects of the lipoic acid. An author concludes that the results obtained allowed to recommend cytoflavin including into CBChAESACL rehabilitative treatment.