The present work analyzes the non-drug methods of primary prevention effects on microcirculatory abnormalities in periodontal tissues in patients with the syndrome of intrauterine growth retardation in past history. It was compared the effectiveness of the exposure of monochromatic red semiconductor laser with exposure of broadband light therapy lamp on the vascular tone of the periodontal tissues by measurement the changes in the nitric oxide concentration in the composition of oral fluid.
The study included two groups of patients, from 17 to 25 years with intrauterine growth retardation in past history, without somatic diseases, without clinical sign of complications of periodontal tissues and hard tissues of the oral cavity.
Patients from the first group underwent the exposure of broadband light therapy lamp on the periodontal tissues and patients of the second one — the impact of low-intensity laser radiation. Biochemical study of the oral fluid of patients was conducted. Oral fluid was collected in the morning on an empty stomach by spitting into the measuring tube, oral fluid was examined before and after the courses of prophylaxis consisting of ten daily sessions of exposure (in accordance with recommendations). Improvement of the biochemical composition of oral fluid was observed in the majority of patients in both groups — 56% at the first group and 62.5% at the second one. Little better effect was mentioned in patients after laser therapy sessions: the content of nitrite and nitrate in the oral fluid with error probability less than 0.05 increased on 14–48% vs 10–28% for patients of first group. The concentration of L-arginine decreased on 6–22% vs 12–26%, respectively, while the level of citrulline increased by 21–59% vs 11–26%. This indicates increasing of the nitric oxide in the periodontal tissues and activation of vasodilatation. Significant changes of the biochemical composition of oral fluid were not fixed in the remaining 44% of the first group patients and 37.5% patients of the second group.